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Research strength in each of our graduate degree tracks is augmented by faculty members whose areas of expertise
overlap more than one area. For example, there is a network of overlapping interests between members of our
Evolution and Genetics groups and between the Cell and Development and the Neurobiology groups. In addition to
the focal emphasis in Cell and Development, Evolution, Genetics and Neurobiology areas, several of our faculty members
use primary plant systems and are organized into a Plant Physiology and Molecular Biology group. Thus, many
faculty members are listed in more than one area.
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Cell and Developmental Biology
Research in Cell and Developmental Biology includes studies on early development and axis formation, cell motility,
the regulation of cell differentiation and gene expression, signal transduction, pattern formation, apoptosis, and
neuronal path-finding. These studies focus on a diverse mix of experimental systems including human tumor and
neuronal cells, yeast, the cellular slime mold Dictyostelium, Xenopus, zebrafish, mice, Arabidopsis, and maize.
A common theme among the laboratories is the use of cellular and molecular biological approaches to understand the
fundamental mechanisms underlying developmental processes.
| Cell and Developmental Biology Faculty |
| Joseph Frankel | Jack Lilien | Diane Slusarski |
| Douglas Houston | Jim Lin | Christopher Stipp |
| Erin Irish | Jonathan Poulton | Joshua Weiner |
| David Soll | |
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Evolution
Evolutionary biologists in the Department of Biology are addressing the most fundamental problems in
Evolution: the origin and evolution of genetic information, the origin of organelles through endosymbiosis, the
evolution of gene and genome structure and composition, intron evolution, the evolutionary consequences of recombination,
the genetic basis of speciation, and the evolution of sexual reproduction and sex chromosomes. Research in Evolutionary Ecology
focuses on the environmental forces that drive genomic changes and ultimately, speciation. The Department is the home
of the Roy J. Carver Center for Comparative Genomics which acts as a focal point for evolutionary research combined
with computational and informatic methods.
| Evolutionary Biology Faculty |
| Debashish Bhattacharya | Stephen Hendrix | Bryant McAllister |
| Josep Comeron | Diana Horton | Jeffry Schabilion |
| Lilach Hadany | John Logsdon | Ming-Che Shih |
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Genetics
Gene expression, DNA replication and the transmission of genetic information are fundamental to all biological
processes. These themes are reflected in the variety of research interests among the participating faculty.
Research programs include studies of gene regulation, meiosis, recombination, and chromosome structure, human
genome mapping, and the use of molecular genomics to investigate population genetics and speciation. Experimental
organisms include yeast, Drosophila, zebrafish, protozoa, algae, maize, and Arabidopsis.
| Genetics Faculty |
| Chi-Lien Cheng | Gary Gussin | John Menninger |
| Josep Comeron | John Logsdon | Ming-Che Shih |
| Daniel Eberl | Robert Malone | Andy Wang |
| Jan Fassler | Bryant McAllister | |
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Neurobiology
Faculty members in the neurobiology group are addressing an array of fundamental problems in development and
function of the nervous system at the systems, cellular and molecular level. These studies include identifying
key molecules involved in axon tracking, dendritic morphology and synapse formation. Other studies are directed at
understanding the relation between the molecular organization of the nervous system and behavior. The tissues and
systems being investigated include the hippocampus, the visual and auditory systems and the organisms include Drosophila,
chickens, mice, and yes, the cockroach.
| Neurobiology Faculty |
| Michael Dailey | Douglas Houston | Christopher Stipp |
| Jeff Denburg | Alan Kay | Joshua Weiner |
| Daniel Eberl | Jack Lilien | Chun-Fang Wu |
| Steven Green | Barbara Stay | |
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Plant Physiology and Molecular Biology
We take corn very seriously in Iowa and it is one of several plant systems being investigated by our Plant
Physiology and Molecular Biology group; others are rice, Arabidopsis and ferns. Investigators are addressing nutrient
and metabolic regulation of gene expression, environmental impacts on plant development, floral and meristem fate, the
biosynthesis of plant defense compounds, and the functional genomics of plant transcriptional regulatory networks.
This group also has a strong evolutionary component with faculty members investigating the origin of plastids and the
evolution of plant genomic regulatory sequences.
| Plant Physiology and Molecular Biology Faculty |
| Debashish Bhattacharya | Diana Horton | Jeffry Schabilion |
| Chi-Lien Cheng | Erin Irish | Ming-Che Shih |
| Stephen Hendrix | Jonathan Poulton | Andy Wang |
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